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Genetics/Environmental Risk

Clements CC*, Engelstad AM*, Wilkinson CL*, Hyde C, Hartney M, Simmons A, Tager- Flusberg H, Jeste S, Nelson CA. Resting state EEG in young children with Tuberous Sclerosis Complex: associations with medications and seizures. Journal of Neurodevelopmental Disorders. Accepted Jan 2025.

 

La Valle C, Davila Mejia G, Wilkinson CL, Baumer N. Examining Concurrent Associations between Gesture Use, Developmental Domains, and Autistic Traits in Toddlers with Down Syndrome. Journal of Speech, Language, and Hearing Research. 2024. Accepted for publication.

Geiger M, Hurewitz SR, Pawlowski K, Baumer NT, Wilkinson CL. Alterations in aperiodic and periodic EEG activity in young children with Down syndrome. Neurobiol Dis. 2024 Oct 1;200:106643. doi: 10.1016/j.nbd.2024.106643. PMID: 39173846; PMCID: PMC11452906.

 

Girault JB, Donovan K, Hawks Z, Talovic M, Forsen E, Elison JT, Shen MD, Swanson MR, Wolff JJ, Kim SH, Nishino T, Davis S, Snyder AZ, Botteron KN, Estes AM, Dager SR, Hazlett HC, Gerig G, McKinstry RC, Pandey J, Schultz RT, St. John T, Zwaigenbaum L, Todorov A, Truong YK, Styner M, Pruett JR Jr., Constantino JN & Piven J for the IBIS Network. (2022). Infant visual brain development and inherited genetic liability in autism. American Journal of Psychiatry. 179(8):573-585. doi: 10.1176/appi.ajp.21101002. PubMed PMID: 35615814; PubMed Central PMCID: PMC9356977. 

 

Burrows CA, Grzadzinski RL, Donovan K, Stallworthy IC, Rutsohn J, St John T, Marrus N, Parish-Morris J, MacIntyre L, Hampton J, Pandey J, Shen MD, Botteron KN, Estes AM, Dager SR, Hazlett HC, Pruett JR Jr, Schultz RT, Zwaigenbaum L, Truong KN, Piven

J, Elison JT. A Data-Driven Approach in an Unbiased Sample Reveals Equivalent Sex Ratio of Autism Spectrum Disorder-Associated Impairment in Early Childhood. Biol Psychiatry. 2022 Oct 15;92(8):654-662. doi: 10.1016/j.biopsych.2022.05.027. Epub 2022 Jun 7. PubMed PMID: 35965107; PubMed Central PMCID: PMC10062179.

 

DiCarlo, G. E., Mabry, S. J., Cao, X., McMillan, C., Woynaroski, T., Harrison, F. E., Reddy,I., Matthies, H. J. G., Flynn, C. R., Wallace, M. T., Wu, H., & Galli, A. (2021). Autism- associated variant in the SLC6A3 gene alters the oral microbiome and metabolism in a murine model. Frontiers in Psychiatry, 12, Article 665351. https://doi.org/knrv.PMID: 33935841

 

Wilkinson CL, Nelson CA. Increased aperiodic gamma power in young boys with Fragile X Syndrome is associated with better language ability. Molecular Autism. 2021 12 (1):17. PMID: 33632320

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Aung, M. T., M Bakulski, K., Feinberg, J. I., F Dou, J., D Meeker, J., Mukherjee, B., Loch-Caruso, R., Ladd-Acosta, C., Volk, H. E., Croen, L. A., Hertz-Picciotto, I., Newschaffer, C. J., & Fallin, M. D. (2021). Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI). Epigenetics, 1–16.

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Bakulski, K. M., Dou, J. F., Feinberg, J. I., Aung, M. T., Ladd-Acosta, C., Volk, H. E., Newschaffer, C. J., Croen, L. A., Hertz-Picciotto, I., Levy, S. E., Landa, R., Feinberg, A. P., & Fallin, M. D. (2021). Autism-Associated DNA Methylation at Birth From Multiple Tissues Is Enriched for Autism Genes in the Early Autism Risk Longitudinal Investigation. Frontiers in Molecular Neuroscience, 14, 775390.

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Barkoski, J. M., Philippat, C., Tancredi, D., Schmidt, R. J., Ozonoff, S., Barr, D. B., Elms, W., Bennett, D. H., & Hertz-Picciotto, I. (2021). In utero pyrethroid pesticide exposure in relation to autism spectrum disorder (ASD) and other neurodevelopmental outcomes at 3 years in the MARBLES longitudinal cohort. Environmental Research, 194, 110495.

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Brieger, K. K., Bakulski, K. M., Pearce, C. L., Baylin, A., Dou, J. F., Feinberg, J. I., Croen, L. A., Hertz-Picciotto, I., Newschaffer, C. J., Fallin, M. D., & Schmidt, R. J. (2021). The Association of Prenatal Vitamins and Folic Acid Supplement Intake with Odds of Autism Spectrum Disorder in a High-Risk Sibling Cohort, the Early Autism Risk Longitudinal Investigation (EARLI). Journal of Autism and Developmental Disorders.

 

Girault, J.B., Swanson, M.R., Meera, S.S., Grzadzinki, R.L., Shen, M.D., Burrows, C.A., Wolff, J.J., Pandey, J., St.John, T., Estes, A., Zwaigenbaum, L., Botteron, K., Hazlett, H., Dager, S.R., Schultz, R.T., Constantino, J.N., Piven, J. for the IBIS Network, 2020.

Quantitative traint variation in ASD probands and toddler sibling outcomes at 24 months. Journal of Neurodevelopmental Disorders, 12:5. doi:10.1186/s11689-020-9308-7

 

Miller*, M., Iosif, A., Young, G.S., Bell, L.J., Schwichtenberg, A. J., Hutman, T., & Ozonoff, S. (2019). The dysregulation profile in preschoolers with a family history of autism spectrum disorder. Journal of Child Psychology & Psychiatry, 60, 516-523. doi:10.1111/jcpp.13003.

 

An Winko W, Nelson CA, Wilkinson CL. Neural response to repeated auditory stimuli and its association with early language ability in male children with Fragile X syndrome. Frontiers in Integrative Neuroscience. 2022 Nov 14;16:987184. doi: 10.3389/fnint.2022.987184. PMID: 36452884; PMCID: PMC9702328.

 

Girault, J., Donovan, K., Hawks, Z., Talovic, M., Forsen, E., Elison, J., Shen, M., Swanson, M., Wolff, J., Kim, S., & others (2022). Infant visual brain development and inherited genetic liability in autism. American Journal of Psychiatry, 179(8), 573–585.

 

Bai, D., Marrus, N., Yip, B. H. K., Reichenberg, A., Constantino, J. N., & Sandin, S. (2020). Inherited Risk for Autism Through Maternal and Paternal Lineage. Biological Psychiatry, 88(6), 480–487.

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Bakulski, K. M., Dou, J. F., Feinberg, J. I., Brieger, K. K., Croen, L. A., Hertz-Picciotto, I., Newschaffer, C. J., Schmidt, R. J., & Fallin, M. D. (2020). Prenatal Multivitamin Use and MTHFR Genotype Are Associated with Newborn Cord Blood DNA Methylation. International Journal of Environmental Research and Public Health, 17(24), E9190.

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Lyall, K., Song, L., Botteron, K., Coroen, L., Dager, S., Fallin, M. D., Hazlett, H., Kauffman, E., Landa, R., Ladd-Acosta, C., Messinger, D., Ozonoff, S., Pandey, J., Piven, J., Schmidt, R., Schultz, R., Stone, W., Newschaffer, C., & Volk, H. (2020). The association between parental age and autism-related outcomes in children at high familial risk for autism. Autism Research, 1-13. 

 

Mordaunt, C.E., Park, B.Y., Bakulski, K.M. et al. (2019). A meta-analysis of two high-risk prospective cohort studies reveals autism-specific transcriptional changes to chromatin, autoimmune, and environmental response genes in umbilical cord blood. Molecular Autism 10, 36 

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Philippat, C., Barkoski, J., Tancredi, D.J., Elms, B., Barr, D., Ozonoff, S., ... & Hertz-Picciotto, I. (2018). Prenatal exposure to organophosphate pesticides and risk of autism spectrum disorder and other non-typical development at 3 years in a high-risk cohort. International Journal of Hygiene and Environmental Health.

 

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